Economic Evaluation of a Personalized Nutrition Plan Based on Omic Sciences Versus a General Nutrition Plan in Adults with Overweight and Obesity: A Modeling Study Based on Trial Data in Denmark

Top Things to Know

Personalized nutrition plans may not significantly improve health outcomes compared to general plans.

Higher costs associated with personalized plans may limit their cost-effectiveness.

The study highlights the need for larger and longer trials to reduce uncertainty about effectiveness and suggests that scaling up interventions could make them more cost-effective.

Summary of Conclusion/Findings

The study evaluated the cost-effectiveness of a personalized nutrition plan (PP) compared to a general nutrition plan (control) in Denmark. The study combined results from a 10-week randomized controlled trial with a validated obesity economic model to estimate lifetime cost-effectiveness. No significant differences in BMI and quality of life between the PP and control group. PP increased costs slightly compared to the control group. The incremental cost-utility ration (ICUR) indicated that PP may not be cost-effective unless intervention costs are reduced.